From Lab to Life: How Research Turns into Real Impact

When people think about scientific research, they often imagine complex equipment, long experiments, and data that only scientists understand. But behind every lab experiment lies a bigger purpose: improving real lives.

As a pharmacy student at RCSI University of Medicine and Health Sciences, I experienced this connection firsthand. During my studies, I carried out research in the RCSI Cancer Bioengineering Lab as part of my thesis work. This gave me the opportunity to see how laboratory science can contribute to real advances in healthcare.

Starting in the Lab

My project focused on developing new materials that could support therapeutic cancer vaccines (adjuvants). These vaccines are different from traditional ones because, instead of preventing disease, they are designed to help the body fight cancer more effectively.

At the centre of this research is alginate, a natural material derived from brown algae. Although simple in origin, it can be modified into tiny gel-like particles with immune-stimulating potential.

In the lab, this involved preparing solutions, carefully mixing components, and analysing the particles using techniques such as DLS and NTA. Small changes in concentration or preparation could completely alter the outcome, which required patience, precision, and problem-solving.

More Than Just Experiments

At first, lab work can feel like simply following steps: weighing chemicals, stirring solutions, and running instruments. But over time, I began to understand the bigger picture. This is where research becomes meaningful — each small experiment contributes to the larger goal of developing life-changing therapeutics.

Challenges Along the Way

Research is not always straightforward. Not every experiment works as expected. Sometimes results are unclear, and methods need to be adjusted and repeated.

During my project, I had to optimise various conditions to achieve stable, effective particles while also reviewing previous studies in this field. This involved testing multiple concentrations and analysing their behaviour. It taught me that failure is not a setback, but an essential part of discovery.

Connecting to Real Life

The most important lesson I learned is that research is never just about the lab.

The materials we develop could one day be used to enhance cancer treatments, improving patient outcomes and quality of life. While my work is still in its early stages, it contributes to a broader effort to make therapies more effective and targeted.

As a future pharmacist, this connection is especially important. It highlights how science, healthcare, and patient care are all deeply linked.

From Student to Scientist

This experience has changed how I view research. It is no longer just something I study — it is something I actively contribute to.

It has also strengthened my interest in pharmaceutical research, showing me how lab innovation can eventually translate into real treatments for patients.

Final Thoughts

Research may begin in the lab, but its impact reaches far beyond it.

Every measurement, every experiment, and every challenge faced is part of a journey toward improving health and saving lives. For students like me, it is a reminder that what we do today in the lab could shape the treatments of tomorrow.

Written by Abdulrahman Alowaihan

Hidden Dublin Treasures

One may notice colourful traffic control boxes around Dublin. The first one was painted back in 2013. A trial run included just 11 traffic signal boxes on Dublin’s Northside as part of the Dublin Canvas project. This inspiration is rooted in David Murtagh’s Australian trip. On his return, he wanted to do the same in Dublin. The trial was a great success. He runs Dublin Canvas on behalf of Dublin City Council. Read more about it here. 900+ boxes across County Dublin were painted by the end of Autumn 2025.

Now, we can spot them here and there. They add a very personal touch to Dublin streets. Some of them refer to a nearby spot or attraction. Foxes are very popular!

Three foxes were spotted near each other in Dublin 9. One being a real one! So, my collection has just begun. Stay tuned for more.

Collins Ave/Artaine/D9

IACR 2026: Science, Communication, and Impact 

 I recently had the opportunity to attend and present my research at the Irish Association for Cancer Research Conference 2026 in Galway. This year was particularly special for me, as I was selected as one of six early-career researchers to take part in the Prof. Patrick G. Johnston Award for Excellence in Cancer Research Outreach. 

This award recognises researchers who can communicate their work clearly to a public audience. Those selected are chosen based on their lay abstracts and take part in a patient communication workshop ahead of the conference. As part of this, I had the opportunity to work closely with patient advocates and cancer survivors, which was an incredibly valuable experience. It challenged me to think beyond science and focus on how to make my research meaningful, accessible, and relevant to the people it ultimately aims to help. 

My presentation at IACR 2026

During the conference, I presented my research as part of this award session, delivering a lay presentation to an audience made up of scientists, patients, and members of the public. 

My research focuses on developing 3D lung models to better understand cancer behaviour and explore new ways to target lung cancer using mRNA-based approaches. Being able to present this work in a way that resonated with a non-scientific audience was both challenging and rewarding. 

Overall, the conference was an inspiring experience. It reinforced the importance of communication in cancer research and reminded me that behind every project are patients and families who are directly impacted by the work we do. 

Until next time,  

Written by Eve O’Donoghue

Hiya! I’m Nicole 

Hi everyone! I am Nicole, and I recently joined Dr. Olga Piskarvera’s team as a research intern for 8 months. I am 21 years old, and I am currently in my 3rd year of my degree in Advanced Therapeutic Technologies at RCSI. It’s essentially a fusion of biomedical science and biotechnology with emphasis on bioinformatics! 

Mochi

 I have always loved science and dreamt of working in a lab since I was a little, so being able to explore both bioinformatics and lab work is an exciting way to explore my curiosity and creativity. I was quite nervous starting out because I didn’t know what to expect, especially in the lab, as I was afraid of making mistakes. However, I am slowly learning and becoming more confident each day! 

Vietnamese beef pho

A few facts about me: I love animals, especially cats, and, of course, I have a cat myself! Her name is Mochi, and she’s a Scottish fold; she has been my little companion since I was 15. One of my favourite foods is Vietnamese beef pho (Aobaba on Capel Street is my go-to!). I also enjoy reading in my spare time. Two of my favourite books are Homeseeking by Karissa Chen and The Hot Zone by Richard Preston. 

I am looking forward to everything I’ll learning during my time with this team! 😊

Written by Nicole Guo

Student placements

Hi everyone!

My name is Maryam Almotawaa, and I’m a 4th-year pharmacy student.

I am working on research to identify a promising tumour-associated antigen for immunotherapy. I used the R2 platform to review datasets, including neuroblastoma and non-small cell lung cancer. I spent some time in the lab observing Lin and Eve working on a Western blot for GPC2, a promising neuroblastoma and non-small cell lung cancer antigen. I was involved in a small part of a Western blot experiment in which I washed the secondary antibody. Even though it wasn’t a big task, it made me realise that even small steps matter and can affect the final result.

Outside my academic life, I really enjoy spending quality time with my friends, whether that’s catching up over coffee or exploring new food spots around Dublin. I also value having time to unwind and recharge, especially after busy academic periods, as it helps me maintain a good balance between my studies and personal life.

All vials contain specific solutions that help confirm protein expression adsorbed onto the PVDF membrane.

Written by Maryam Almotawaa

Rabia Saleem: My Portuguese Journey

I’m in my third year of a PhD at RCSI and recently completed an RCSI-funded secondment. Reflecting on it, it has been one of my most enjoyable and valuable experiences so far. Coming back to Ireland after the secondment feels great. I’m feeling refreshed and eager to dive back into my work.

I spent my placement at the University of Lisbon’s Department of Pharmacy, working in Prof. Helena Florindo’s lab. Everyone was super welcoming, which made it easy to settle in and get started without any stress.

Most of my time in the lab was spent preparing biodegradable nanoparticles using a peptide from my project. I also got to run some ex vivo experiments and even joined in on in vivo work under supervision, a completely new and really exciting experience for me. The best part was seeing some promising results come through, which was really encouraging.

Outside the lab, Lisbon was just a lovely place to spend time. I picked up a little Portuguese, enjoyed the sunshine, and appreciated the relaxed pace.

Now that I’m back, I’m excited to finish up the last bits of my project and build on what I learned during the secondment. Overall, it was an amazing experience, both for my research and personally.

Written by Rabia Saleem, the IRC PhD student

Looking at Brain Tumors, One slice at a Time 

’m writing to you from the Biomedicum, a research facility at the University of Helsinki. As you can probably guess, I didn’t travel here for the Finnish weather, but to collaborate with a team that is part of the European Mac4Me consortium. This group specialises in a fascinating imaging technique called multiplex immunohistochemistry. In simple terms, they take patient tissue samples or samples created in the lab and cut them into incredibly thin slices—just 4 micrometres thick, which is about 4/100ths of a millimetre. They then use multiple rounds of staining with antibodies to visualise different tumour markers and map out exactly where these markers are located within the sample. You can see an example of this stained tissue below. 

Cutaneous squamous cell carcinoma samples stained for 4 different markers using multiplex immunohistochemistry. 
Viiklepp K Journal of Investigative Dermatology. 2025 

For this project, I brought along different versions of a “brain-like” hydrogel I’ve created in the lab. These hydrogels have varying stiffness and molecular compositions, and they contain Neuroblastoma tumour cells growing within them (you can see simple cell staining below). My goal here is to use the lab’s advanced imaging machine to observe how these tumour cells behave. I want to see if they are multiplying, if they seem stressed or healthy, and how they adapt to the different molecular environments of the hydrogels. 

This approach will be incredibly valuable for studying how the tumour’s surroundings—the microenvironment—influence the spread of Neuroblastoma to the brain. It will also help us understand what happens when we add new molecular components to the hydrogel to more closely mimic the brain environment. Looking ahead, I plan to use this same technique for an even more complex experiment: by growing immune cells together with the neuroblastoma cells, I hope to visualise and identify the specific pathways the cancer cells use to communicate with and potentially suppress the immune system. 

Neuroblastoma cell line (in blue) in a hyaluronic acid-based hydrogel. Day 1 left and day 5 right. 

Written by Pierluca Cancellieri, Mac4Me MSCA PhD

My 1st Mac4Me Secondment – Nottingham 2026

It’s great to be back! Returning to the University of Nottingham for my secondment with PeptiMatrix feels like coming full circle since finishing my undergrad here.

Stepping into the lab felt instantly familiar. Because I already knew the layout, I could breeze through the initial induction and training and get straight into the exciting part: the science.

I have to say, the lab is so well-organised, and it’s packed with some impressive new kit. I’ve already spotted an automated cell culture system and a 3D printer, but the equipment I’m most excited about is the rheometer, which will be central to my project.

I also got hands-on right away, learning how to make peptide hydrogels and even how to encapsulate cells into them. It’s amazing to see the building blocks of tissue engineering coming together right before my eyes.

There are plenty more cool things planned for the coming weeks. I’ll be sure to keep you updated on the journey.

Written by Chunyu Yan, Mac4Me PhD student

Two New-Minted PhD in 2025!

What a year – two young and talented postgraduate students have been minted with a Doctor of Philosophy Degree in September and December of 2025. They are Dr Lin Ma and Dr Ronja Struck. Hard work and dedication are the cornerstones of this challenging but rewarding journey.

They sailed through scattered showers and sunny spells, gale winds and stormy snow with sunshine developing elsewhere, turning chilly under clear skies on some days with temperatures below/above zero. The full spectrum of emotions and hard work was spiced up by the uncertainty of COVID-19 restrictions. Well done to Ronja and Lin!

My greatest thanks to Lin’s examiners Prof Sue Burchill (University of Leeds, UK),  Dr Joan Ní Gabhann-Dromgoole  (RCSI, Ireland) and the independent chair Prof Kevin McGuigan (RCSI, Ireland)!!

My greatest thanks to Ronja’s examiners, Prof Martina Rauner (Dresden University, Germany), Prof Fabio Quondamatteo (RCSI, Ireland) and the independent chair Dr Inmar Schoen (RCSI, Ireland)!!

This work would not be possible without the generous support from the Irish Research Council (Research Ireland) and the Conor Foley Neuroblastoma Cancer Research Foundation to Ronja, and from the RCSI-Soochow University StAR International PhD Programme to Lin.

Hi Everyone! I’m Anusha

Hi, I am Anusha from India. I recently joined Dr Olga’s team at RCSI as a research fellow.  I completed my PhD in the development of nanomaterials for image-assisted cancer therapy. After that, I had an amazing run as a research scientist for 7 years, working in cancer immunotherapy. Work focused on the development of nanomaterials for the delivery of immunomodulatory drugs and on engineered adjuvants for therapeutic cancer vaccines. Then came my lil son Aadi, and I took a two-year break. When I was actively looking for positions after my break, I thought of writing a Marie Curie grant, and that’s how I met Dr Olga. Dr Olga then offered me a position at RCSI to work on neuroblastoma. I am just incredibly grateful for this opportunity and to be part of an amazing team, especially after being away from the lab for a while. It’s a new role, a whole new world here in Dublin, and I am waiting to see what exciting things come next.  

Falling in love with the Irish coast @ Donabate 

Written by Anusha Ashokan