September 2016 archive

Sep 24

How we work with cancer cell lines?

How we work with cancer cell lines? The very first human cancer cell line was developed from a patient with an aggressive cervical cancer in 1951. This cell line was called HeLa after the patient name – Henrietta Lacks. This is the most popular and robust cancer cell line in biomedical research. Since then, other …

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Sep 18

Drug resistant neuroblastoma cells

Children with neuroblastoma undergo several cycles of intensive chemotherapy to stop disease progression with the final aim to eliminate the tumour. Chemotherapy includes carboplatin or cisplatin in various combinations with drugs such as cyclophosphamide, ifosfamide, doxorubicin, etoposide, topotecan and vincristine (1). Nevertheless, in average 1 in 5 children with stage 4 disease do not respond …

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Sep 10

Cell to Cell Communicators

Tumour cells send different types of messages from one cell to another aka people post letters, postcards, and parcels to their families, friends, colleagues or  business. Cells can direct their messages using free moving proteins – postcards. They can wrap it in microvesicles with different cargo. Big microvesicles can take up big messages – parcels, small …

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Sep 01

Childhood Cancer Awareness Month

September is Childhood Cancer Awareness Month! Facts about childhood cancer Childhood cancer is 1% of all newly diagnosed cancers globally (1,2). It is the second most common cause of death among children under age of 19 after accidents. Childhood cancer is an umbrella term for a great variety of malignancies which vary by site of …

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