Meet a philosopher in the lab

I just spent September in Dublin for a research visit to the Cancer Bioengeneering group as part of the Mac4Me project. The project brings together researchers who develop models that we can use in cancer research, including on neuroblastoma. My role is a bit different. I’m do philosophy research, and my project is about how we should involve patients in cancer research. I was particularly interested in what patient involvement might look like in research on neuroblastoma and childhood cancer.

One of the things I did during my stay was shadowing. That basically means following someone around in the lab and watching what they do. I followed Pierluca, who showed me how he grows cells in plastic containers. At one point, he had to “split” the cells. This involves adding an enzyme that makes the cells detach from the bottom of the container, before transferring some of them to a new one where they can continue growing. Apparently cancer cells like to stick to the plastic.

For me, this was quite exotic. Back in Rotterdam, I spend most of my working days in front of a computer.

Microscopic examination of cells

Another thing that surprised me was how old some of the computer screens looked. You have these very expensive machines, sometimes costing hundreds of thousands of euros, connected to screens that look like they’re from the early 2000s. I’ve noticed this in other labs too.

RCSI do a lot of patient involvement stuff. Ireland has actually come further than a lot of other countries when it comes to patient involvement. At the same time, lab researchers that I speak to find it hard to do patient involvement, even if they want to do it.

In Dublin (Howth), we walked 112 km for neuroblastoma; it was very beautiful.

Outside the lab, I developed a nice lunch routine: buying something at Dunnes (pizza!) and bringing it to St Stephen’s Green, just next to RCSI, whenever the sun was out, and also when it wasn’t, which was most days during my stay, unfortunately.

Another day in St. Stephen’s park. I was eating lunch and was asked to move by the man wearing the leather outfit, who happens to be a dog photographer.

Written by Simon Gramvik, Mac4Me MSCA DN

Hi! I’m Alannah

Hi! I’m Alannah, and I’ve recently joined Dr Olga Piskareva’s research group at RCSI to begin my PhD! I’m originally from Wicklow, Ireland, and completed both my BSc in Biotechnology and MSc in Diagnostics and Precision Medicine at Dublin City University (DCU).

Throughout my studies, I developed a particular interest in cancer biology and precision medicine, especially the potential for research to improve how we understand and treat cancer. Having previously worked on melanoma research, I’m really excited to explore a new area of cancer research, develop new skills, and take on the challenges that come with starting a PhD. I’m looking forward to seeing where the next few years take me!

Outside the lab, I love travelling, exploring new places, and making the most of any opportunity for an adventure! I particularly enjoy spending time outdoors, whether that involves hiking, discovering somewhere new, or just getting out and staying active. When I’m not travelling or in the lab, I also teach piano lessons, something I’ve been doing for several years and really enjoy!

I’m really looking forward to this new chapter and all the exciting experiences and opportunities ahead!

Written by Alannah O’Neill

Hi everyone! I’m Isabelle

Hi everyone! I’m Isabelle. I’m 24 years old, and I’ve recently joined Dr Olga Piskareva’s group to start my PhD. I’m originally from Germany, where I completed both my Bachelor’s and Master’s degrees before moving on to this new adventure.

My interest in science goes back further than I can remember, but one of my earliest memories is taking part in a microscopy course when I was in fifth grade. I found it fascinating to discover a whole new world through a microscope, and looking back, it’s quite nice to think that my curiosity back then eventually led me to where I am today! I’m excited to deepen my knowledge, take on new challenges, and see where this PhD journey takes me.

Outside the lab, I enjoy cooking, staying active through sports, reading, and catching up with friends. I’m always happy to find a good book to get lost in, and one of my favourites is The Love Hypothesis by Ali Hazelwood, which I absolutely loved!

I’m really looking forward to this new chapter, learning from everyone in the group, and getting to know everyone better! 😊

Written by Isabelle Pakulla, POI-2 PhD Student

We Reached Our Fundraising Goal

We started our fundraising in June with the VHI Women’s Mini-Marathon and cocluded with a PubQuiz. We raised 1K to be split between two amazing charities that support neuroblastoma research: the Conor Foley Neuroblastoma Cancer Research Foundation and Neuroblastoma UK.

We thank all our supporters for their generous donations!